Inhibition of Invasive Salmonella by Orally Administered IgA and IgG Monoclonal Antibodies
A. F. Richards, J. Doering, S. A. Lozito, J. Varrone, M. Pauly, K. Whaley, L. Zeitlin, N. J. Mantis
This study shows orally administered IgA and SIgA monoclonal antibodies can reduce Salmonella Typhimurium uptake in Peyers patches, while IgG is less effective, highlighting the need for improved formulations to sustain mAb activity in the gut.
bioRxiv · Sep 23, 2019Immunology