Author

K. Whaley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Organism:non-human primate· 2 Research Focus:benchmarking· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

L. Zeitlin· 3 shared C. J. Roy· 2 shared L. Doyle-Meyers· 2 shared A. F. Richards· 1 shared D. Ehrbar· 1 shared D. Kim· 1 shared D. Verreault· 1 shared E. Vitetta· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

L. Zeitlin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibition of Invasive Salmonella by Orally Administered IgA and IgG Monoclonal Antibodies

A. F. Richards, J. Doering, S. A. Lozito, J. Varrone, M. Pauly, K. Whaley, L. Zeitlin, N. J. Mantis

This study shows orally administered IgA and SIgA monoclonal antibodies can reduce Salmonella Typhimurium uptake in Peyers patches, while IgG is less effective, highlighting the need for improved formulations to sustain mAb activity in the gut.

bioRxiv · Sep 23, 2019Immunology

Therapeutic Treatment of Aerosolized Staphylococcal Enterotoxin B in Nonhuman Primates with two Monoclonal Antibodies

D. Verreault, J. Ennis, K. Whaley, S. Killeen, H. Karauzum, J. Aman, R. Holtsberg, L. Doyle-Meyers, P. Didier, L. Zeitlin, C. J. Roy

Two monoclonal antibodies were tested for therapeutic efficacy against aerosolized SEB in a nonhuman primate model, showing survival in treated animals compared to untreated controls.

bioRxiv · Sep 23, 2018 · PreprintImmunology

A Humanized Monoclonal Antibody against the Enzymatic Subunit of Ricin Toxin Rescues Rhesus macaques from the Lethality of Aerosolized Ricin

C. J. Roy, D. Ehrbar, N. Bohorova, O. Bohorov, D. Kim, M. Pauley, K. Whaley, Y. Rong, F. J. Torres-Velez, E. Vitetta, P. J. Didier, L. Doyle-Meyers, L. Zeitlin, N. Mantis

This study shows that huPB10, a humanized monoclonal antibody, can rescue rhesus macaques from lethal ricin exposure when administered within four hours of aerosolized ricin exposure.

bioRxiv · Sep 6, 2018 · PreprintImmunology