Author

S. Akilesh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

J. Himmelfarb· 2 shared A. Johnson· 1 shared A. Reynolds· 1 shared C. E. Alpers· 1 shared C. K. Yeung· 1 shared C. P. Miller· 1 shared D. Bates· 1 shared D. Dunn· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

J. Himmelfarb

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Author profile →

3 papers

Recent·Most cited

Digital Spatial Profiling of Collapsing Glomerulopathy

K. D. Smith, K. Henriksen, R. F. Nicosia, C. E. Alpers, S. Akilesh

This study uses digital spatial profiling to analyze transcriptional heterogeneity in collapsing glomerulopathy lesions from HIV and SARS-CoV-2 infected patients.

Kidney International · May 1, 2022Peer-reviewedPathology

Multi-omic Characterization of Human Tubular Epithelial Cell Response to Serum

K. A. Lidberg, S. Muthusamy, M. Adil, R. S. Patel, L. Wang, T. K. Bammler, J. Reichel, C. K. Yeung, J. Himmelfarb, E. J. Kelly, S. Akilesh

The paper characterizes the transcriptional and epigenomic response of human tubular epithelial cells to serum exposure, identifying key regulatory programs and gene signatures.

bioRxiv · Jan 29, 2021Cell Biology

Cryptic Promoter Activation Drives POU5F1 (OCT4) Expression in Renal Cell Carcinoma

K. T. Siebenthall, C. P. Miller, J. D. Vierstra, J. Mathieu, M. Tretiakova, A. Reynolds, R. Sandstrom, E. Rynes, S. J. Neph, E. Haugen, A. Johnson, J. Nelson, D. Bates, M. Diegel, D. Dunn, , S. Akilesh

The paper identifies a HIF-pathway-responsive cryptic promoter driving POU5F1 expression in RCC, linked to poor patient outcomes.

bioRxiv · Jul 27, 2018Cancer Biology