A high-carbohydrate diet prolongs dysbiosis and Clostridioides difficile carriage and increases late-onset CDI and mortality in a hamster model of infection
S. Bhute, C. C. Mefferd, J. R. Phan, M. Ahmed, A. E. Fox-King, S. Alarcia, J. V. Villarama, E. Abel-Santos, B. P. Hedlund
This study shows a high-carbohydrate diet worsens Clostridioides difficile infection in hamsters by causing prolonged dysbiosis, persistent carriage, and higher mortality compared to a standard diet.
bioRxiv · Oct 4, 2021 · PreprintMicrobiology