B. P. Hedlund

A high-carbohydrate diet prolongs dysbiosis and Clostridioides difficile carriage and increases late-onset CDI and mortality in a hamster model of infection

This study shows a high-carbohydrate diet worsens Clostridioides difficile infection in hamsters by causing prolonged dysbiosis, persistent carriage, and higher mortality compared to a standard diet.

Recoding enhances the metabolic capabilities of two novel methylotrophic Asgardarchaeota lineages

This study identifies two new Asgardarchaeota lineages with methylotrophic metabolism enhanced by genetic code expansions, including selenocysteine and pyrrolysine recoding.

Ancestral absence of electron transport chains in Patescibacteria and DPANN

The paper investigates Patescibacteria and DPANN, finding they lack electron transport chains and rely on fermentation, suggesting ancestral adaptations to symbiotic lifestyles.

Diversity and Distribution of a Novel Genus of Hyperthermophilic Aquificae Viruses Encoding a Proof-reading Family-A DNA Polymerase

The paper describes novel hyperthermophilic Aquificae viruses with unique genomic features and proposes a new genus based on their distinct replication strategy and gene-sharing networks.

Microbiome shifts associated with the introduction of wild Atlantic horseshoe crabs (Limulus polyphemus) into a touch-tank exhibit

The paper tracks microbiome changes in wild and tank-acclimated Atlantic horseshoe crabs over time, finding a rapid decline in microbial diversity and an increase in opportunistic pathogens in captivity.

A high-fat/high-protein, Atkins-type diet exacerbates Clostridioides (Clostridium) difficile infection in mice, whereas a high-carbohydrate diet protects

This study shows that a high-fat/high-protein diet worsens C. difficile infection in mice, while a high-carbohydrate diet protects against it.