Structural insights into acetylated histone ligand recognition by the BDP1 bromodomain of Plasmodium falciparum
A. K. Singh, M. Phillips, S. Alkrimi, M. Tonelli, S. P. Boyson, K. L. Malone, J. C. Nix, K. C. Glass
This study investigates the binding specificity of PfBDP1 bromodomain to acetylated histones in P. falciparum, revealing its preference for tetra-acetylated H4 and potential therapeutic implications.
bioRxiv · Aug 2, 2022Biophysics