S. Allam

The Colibactin-Producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance.

This study shows that Colibactin-producing Escherichia coli creates an immunosuppressive lipid-rich tumor microenvironment that promotes colorectal cancer progression and chemoresistance.

The molecular determinants of R-roscovitine block of hERG channels

This study investigates how R-roscovitine inhibits hERG channels by analyzing mutations and IC50 values, suggesting some residues are critical while others are not, with implications for drug screening and CiPA guidelines.