The P2Y2 Nucleotide Receptor Mediates Monocyte Tissue Factor Expression and Endotoxemia Death in Mice
Q. Peng, S. Qian, S. Alqahtani, P. Panizzi, J. Shen
This study shows that the P2Y2 receptor in monocytes increases tissue factor expression, contributing to endotoxemia death in mice, and suggests it as a potential drug target.
bioRxiv · Dec 28, 2021 · PreprintPharmacology & Toxicology