Cathepsin G Degrades Synovial Fluid Lubricin: Relevance For Osteoarthritis Pathogenesis
S. Huang, K. A. Thomsson, C. Jin, S. Alweddi, A. Struglics, O. Rolfson, L. I. Bjorkman, S. Kalamajsk, T. A. Schmidt, G. D. Jay, R. Krawetz, N. G. Karlsson, T. Eisler
This study shows that cathepsin G degrades lubricin in synovial fluid, contributing to osteoarthritis pathogenesis by reducing joint lubrication.
bioRxiv · Oct 15, 2019 · PreprintPathology