Cancer BiologybioRxivPreprint
MAP Kinase inhibition reshapes tumor microenvironment of mouse pancreatic cancer by depleting anti-inflammatory macrophages
P. Delfino, C. Neander, D. Filippini…·V. Corbo
This study shows that MEK inhibition in mouse pancreatic cancer reduces anti-inflammatory macrophages and enhances gemcitabine efficacy by altering the tumor microenvironment.
DOI 10.1101/759779