Blocking the Rac1-TRPC5 pathway protects human podocytes
Y. Zhou, C. Kim, J. L. B. Pablo, F. Zhang, J. Y. Jung, L. Xiao, S. Bazua, M. Emani, C. Hopkins, A. Weins, A. Greka
This study shows TRPC5 inhibition protects human podocytes from injury in vitro and in vivo, supporting its therapeutic potential for kidney diseases.
bioRxiv · Aug 28, 2020 · PreprintCell Biology