Author

S. C. Iyer

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Cancer Biology· 1

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Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. A. Martinez· 1 shared E. Domingo· 1 shared J. A. Bridgewater· 1 shared J. N. Primrose· 1 shared L. F. Spurr· 1 shared M. C. Posner· 1 shared M. I. D'Angelica· 1 shared M. Talamonti· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

C. A. Martinez

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1 paper

Recent·Most cited

Chromosomal instability mediates immune exclusion and response to cytotoxic chemotherapy in colorectal liver metastases

C. A. Martinez, L. F. Spurr, S. C. Iyer, S. A. Pugh, J. A. Bridgewater, J. N. Primrose, E. Domingo, T. S. Maughan, M. I. D'Angelica, M. Talamonti, M. C. Posner, P. P. Connell, R. R. Weichselbaum, S. P. Pitroda

This study shows that chromosomal instability (CIN) in colorectal liver metastases leads to immune exclusion and poor prognosis but increases sensitivity to DNA-damaging therapies.

bioRxiv · Sep 22, 2021 · PreprintCancer Biology