Author

T. S. Maughan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Lewis· 1 shared C. A. Martinez· 1 shared C. Holmes· 1 shared C.-H. Wu· 1 shared E. Domingo· 1 shared J. A. Bridgewater· 1 shared J. N. Primrose· 1 shared L. F. Spurr· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Lewis

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2 papers

Recent·Most cited

Chromosomal instability mediates immune exclusion and response to cytotoxic chemotherapy in colorectal liver metastases

C. A. Martinez, L. F. Spurr, S. C. Iyer, S. A. Pugh, J. A. Bridgewater, J. N. Primrose, E. Domingo, T. S. Maughan, M. I. D'Angelica, M. Talamonti, M. C. Posner, P. P. Connell, R. R. Weichselbaum, S. P. Pitroda

This study shows that chromosomal instability (CIN) in colorectal liver metastases leads to immune exclusion and poor prognosis but increases sensitivity to DNA-damaging therapies.

bioRxiv · Sep 22, 2021 · PreprintCancer Biology

A metagene of NRF2 expression is a prognostic biomarker in all stage colorectal cancer

S. O'Cathail, C.-H. Wu, A. Lewis, C. Holmes, M. Hawkins, T. S. Maughan

The paper defines an NRF2 metagene and shows it predicts poor prognosis in all stages of colorectal cancer, with higher expression in CMS4 subtype.

bioRxiv · Jul 2, 2019 · PreprintCancer Biology