Author

S. C. Ortiz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:fungi (other)· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

C. M. Hull· 2 shared A. Frerichs· 1 shared A. J. Thom· 1 shared H. Gage· 1 shared J. Davies· 1 shared M. Bertuzzi· 1 shared M. C. McKeon· 1 shared M. Huang· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

C. M. Hull

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cryptococcus displays spore-specific invasion of alveolar epithelial cells

S. C. Ortiz, R. Fortune-Grant, A. J. Thom, J. Davies, R. C. May, R. A. Drummond, M. Bertuzzi

This study shows Cryptococcus spores invade alveolar epithelial cells in vitro and in vivo, suggesting these cells may serve as an intracellular niche for dissemination and latency.

bioRxiv · Dec 14, 2023 · PreprintMicrobiology

Spores of the fungal pathogen Cryptococcus exhibit cell type-specific carbon source utilization during germination

S. C. Ortiz, M. C. McKeon, M. R. Botts, H. Gage, A. Frerichs, C. M. Hull

This study characterizes Cryptococcus spore germination by analyzing carbon source utilization and identifies a spore-specific trehalase enzyme essential for germination under trehalose conditions.

bioRxiv · Oct 1, 2023 · PreprintMicrobiology

Discovery of fungal-specific targets and inhibitors using chemical phenotyping of pathogenic spore germination

S. C. Ortiz, M. Huang, C. M. Hull

The paper identifies fungal-specific inhibitors of spore germination through chemical phenotyping and characterizes their mechanisms, revealing potential antifungal targets.

bioRxiv · Feb 6, 2021Microbiology