Mycobacterium tuberculosis canonical virulence factors interfere with a late component of the TLR2 response.
A. E. Hinman, C. Jani, S. C. Pringle, W. R. Zhang, N. Jain, A. J. Martinot, A. K. Barczak
The paper identifies a late TLR2-dependent transcriptional response in macrophages to Mycobacterium tuberculosis mutants and shows how virulence factors interfere with this response to promote TB pathogenesis.
bioRxiv · Oct 6, 2021 · PreprintMicrobiology