Author

C. Jani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. K. Barczak· 2 shared N. Jain· 2 shared A. E. Hinman· 1 shared A. J. Martinot· 1 shared A. Marsh· 1 shared D. E. Root· 1 shared J. G. Doench· 1 shared O. Glover· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

A. K. Barczak

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Vps18 contributes to phagosome membrane integrity in Mycobacterium tuberculosis-infected macrophages.

C. Jani, A. Marsh, P. Uchil, N. Jain, Z. R. Baskir, O. Glover, D. E. Root, J. G. Doench, A. K. Barczak

This study identifies Vps18 as a host factor critical for maintaining phagosomal membrane integrity in Mtb-infected macrophages, showing increased phagosomal damage and reduced antibiotic efficacy in its absence.

bioRxiv · Oct 1, 2023 · PreprintMicrobiology

Mycobacterium tuberculosis canonical virulence factors interfere with a late component of the TLR2 response.

A. E. Hinman, C. Jani, S. C. Pringle, W. R. Zhang, N. Jain, A. J. Martinot, A. K. Barczak

The paper identifies a late TLR2-dependent transcriptional response in macrophages to Mycobacterium tuberculosis mutants and shows how virulence factors interfere with this response to promote TB pathogenesis.

bioRxiv · Oct 6, 2021 · PreprintMicrobiology