Cysteine: an ancestral Cu binding ligand in green algae?
D. Strenkert, S. Schmollinger, Y. Hu, C. Hofmann, K. Holbrook, H. W. Liu, S. O. Purvine, C. D. Nicora, S. Chen, M. S. Lipton, T. R. Northen, S. Clemens, S. S. Merchant
The paper shows that cysteine is an ancestral Cu(I) ligand in Chlamydomonas reinhardtii, as Zn deficiency disrupts Cu homeostasis and increases cysteine levels, which co-localize with Cu in acidocalcisomes.
bioRxiv · Mar 15, 2023 · PreprintBiochemistry