S. S. Merchant

Chlamydomonas cells transition through distinct Fe nutrition stages within 48 h of transfer to Fe-free medium

This study examines how Chlamydomonas cells adjust to Fe-free conditions, showing rapid transcriptomic changes and slower metabolic shifts.

Mutation of negative regulatory gene CEHC1 encoding an FBXO3 protein results in normoxic expression of HYDA genes in Chlamydomonas reinhardtii

The paper identifies a mutation in CEHC1, which encodes FBXO3, leading to normoxic expression of HYDA genes in Chlamydomonas reinhardtii by stabilizing CRR1.

Scarcity of fixed carbon transfer in a model microbial phototroph-heterotroph interaction

This study quantifies carbon transfer in a microbial alga-bacterium interaction, finding limited carbon flow and bacterial vitamin B12 synthesis despite algal lysis.

Distinct function of Chlamydomonas CTRA-CTR transporters in Cu assimilation and intracellular mobilization

This study identifies distinct roles of CTR1 and CTR2 in Cu import and mobilization in Chlamydomonas, with CTR1 mediating high-affinity uptake and CTR2 facilitating Cu remobilization under Zn deficiency.

Cysteine: an ancestral Cu binding ligand in green algae?

The paper shows that cysteine is an ancestral Cu(I) ligand in Chlamydomonas reinhardtii, as Zn deficiency disrupts Cu homeostasis and increases cysteine levels, which co-localize with Cu in acidocalcisomes.

Chlamydomonas ATX1 is essential for Cu distribution towards the secretory pathway and maintenance of biomass in conditions demanding cupro-enzyme dependent metabolic pathways

This study identifies CrATX1 in Chlamydomonas as essential for copper distribution to the secretory pathway and biomass maintenance under conditions requiring cupro-enzyme metabolic pathways.

Single-cell Visualization and Quantification of Trace Metals in Chlamydomonas Lysosome-Related Organelles

The paper uses XFM to quantify trace metal storage in Chlamydomonas acidocalcisomes under metal over-accumulation, showing Fe and Cu sequestration and distinct organelle populations.

Co-Expression Networks in the Green Alga Chlamydomonas reinhardtii Empower Gene Discovery and Functional Exploration

The paper identifies co-expression relationships in Chlamydomonas reinhardtii genes and highlights batch culture synchronization as a source of variation.