Paternal obesity and epigenetic inheritance of breast cancer: The role of systemic effects and transmission to the second generation
C. C. Fontelles, R. S. da Cruz, A. K. Gonsiewski, E. Barin, V. Tekmen, L. Jin, M. I. Cruz, O. Loudig, A. Warri, S. de Assis
This study shows paternal obesity increases breast cancer risk in female offspring and this predisposition can be passed to the next generation through altered sperm tRNA fragments.
bioRxiv · Jun 5, 2020Cancer Biology