Cancer BiologybioRxiv
Tumor Necrosis Factor Receptor Signaling Modulates Carcinogenesis in a Mouse Model of Breast Cancer
L. He, K. Bhat, S. Duhacheck-Muggy…·F. Pajonk
This study shows that reducing TNFR2 signaling in mice increases breast cancer incidence and aggressiveness, suggesting TNFR2 agonists could help prevent breast cancer in high-risk populations.
DOI 10.1016/j.neo.2020.12.007