ATM phosphorylates PP2A subunit A resulting in nuclearexport and spatiotemporal regulation of the DNA damageresponse
A. Sule, S. E. Golding, S. F. Farhan, J. Watson, M. H. Ahmed, G. E. Kellogg, T. Bernas, S. Koebley, J. C. Reed, L. F. Povirk, K. Valerie
This study shows ATM phosphorylates PR65 at S401, regulating DDR by controlling PR65 nuclear-cytoplasmic shuttling and affecting DSB repair and cell survival.
bioRxiv · Aug 29, 2021Cancer Biology