S. E. Heiden

In-host evolution of classic to convergent Klebsiella pneumoniae sequence type 147 isolates and impact of associated capsular changes on different morphotypes

This study investigates in-host evolution of Klebsiella pneumoniae sequence type 147 isolates, revealing microevolution from classic to convergent pathotype through plasmid acquisition and capsular changes affecting virulence and morphology.

Temperatures above 37°C increase virulence of a convergent Klebsiella pneumoniae sequence type 307 strain

This study shows that temperatures above 37°C increase hypermucoviscosity and virulence in a convergent Klebsiella pneumoniae strain, potentially due to plasmid-encoded factors and temperature-dependent regulatory changes.

Klebsiella pneumoniae exhibiting a phenotypic hyper-splitting phenomenon including the formation of small colony variants

The paper describes a Klebsiella pneumoniae strain exhibiting phenotypic hyper-splitting, forming small colony variants and multiple morpho-resistotypes with clinical implications.

Multi-omics investigations uncover unique pathogenic markers in clinical Klebsiella pneumoniae that could be leveraged as novel antimicrobial targets

This study identifies unique pathogenic markers in Klebsiella pneumoniae through multi-omics analysis, suggesting potential novel antimicrobial targets.

Carbapenem- and cefiderocol-resistant Enterobacterales in surface waters in Kumasi, Ashanti Region, Ghana

The study found carbapenem-resistant Enterobacterales in surface waters in Ghana, with some isolates also showing resistance to cefiderocol.