S. Elowe

ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression

This study shows TEM4 regulates the cell cycle by controlling G1 progression through modulation of p21waf1/cip1 and cyclin B levels.

The substrate quality of CK2 target sites has a determinant role on their function and evolution

The paper investigates how substrate quality affects the function and evolution of CK2 phosphosites, showing that optimal sites are more conserved and functionally important than minimal ones.

A Commercial ARHGEF17/TEM4 antibody cross-reacts with Nuclear Mitotic Apparatus protein 1 (NuMA)

The study identifies cross-reactivity of a TEM4 antibody with NuMA, affecting experimental interpretations in immunocytochemistry and immunoprecipitation.

An unbiased, quantitative and versatile method for determining misaligned and lagging chromosome during mitosis

The paper develops and validates a geometric method to quantify chromosome misalignment and lagging chromosomes during mitosis using ImageJ2/Fiji pipelines.

The BUBR1 pseudokinase domain promotes efficient kinetochore PP2A-B56 recruitment to regulate spindle checkpoint silencing and chromosome alignment

This study shows the BUBR1 pseudokinase domain enhances PP2A-B56 recruitment to kinetochores, ensuring proper checkpoint silencing and chromosome alignment by modulating phosphorylation.