Photoimmunotherapy retains its anti-tumor efficacy with increasing stromal content in heterotypic pancreatic cancer spheroids
M. A. Saad, W. Zhung, M. E. Stanley, S. Formica, S. G. Garcia, G. Obaid, T. Hasan
This study evaluates photoimmunotherapy (PIT) and Visudyne(R)-PDT in PDAC spheroids with varying stromal content, showing PIT retains efficacy while Visudyne(R)-PDT becomes less effective as stromal content increases.
bioRxiv · Nov 9, 2021 · PreprintCancer Biology