Author

T. Hasan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. A. Saad· 3 shared A. A. Sweeney· 1 shared A. Palanisami· 1 shared A. U. Ahmed· 1 shared B. Q. Spring· 1 shared C. D. James· 1 shared C. H. Park· 1 shared C. M. Horbinski· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersCancer Biology

M. A. Saad

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Dual Function Antibody Conjugate Enabled Photoimmunotherapy Complements Fluorescence and Photoacoustic Imaging of Head and Neck Cancer Spheroids

M. A. Saad, S. Grimaldo-Garcia, A. A. Sweeney, S. Mallidi, T. Hasan

This paper evaluates a dual function antibody conjugate for imaging and treating head and neck cancer spheroids, showing improved detection with photoacoustic imaging and effective PIT response.

bioRxiv · Jan 30, 2023Cancer Biology

Sparse-spectral microendoscopy for real-time visualization of tumor cell phenotype and microenvironment spatial heterogeneity in vivo

B. Q. Spring, A. Palanisami, M. A. Saad, E. M. Kercher, R. T. Lang, R. C. Harman, J. Sutin, Z. Mai, T. Hasan

This paper introduces a real-time imaging technique to visualize tumor cell phenotype and microenvironment spatial heterogeneity in vivo, revealing spatial correlations and treatment responses.

bioRxiv · Jun 17, 2022 · PreprintBioengineering

Pulsed transistor operation enables miniaturization of electrochemical aptamer based sensors

S. L. Bidinger, S. T. Keene, S. Han, K. W. Plaxco, G. G. Malliaras, T. Hasan

This paper demonstrates pulsed transistor operation in electrochemical aptamer-based sensors, achieving larger current modulation and scalable signal amplification compared to electrode-based biosensors.

bioRxiv · Jun 9, 2022Bioengineering

Photoimmunotherapy retains its anti-tumor efficacy with increasing stromal content in heterotypic pancreatic cancer spheroids

M. A. Saad, W. Zhung, M. E. Stanley, S. Formica, S. G. Garcia, G. Obaid, T. Hasan

This study evaluates photoimmunotherapy (PIT) and Visudyne(R)-PDT in PDAC spheroids with varying stromal content, showing PIT retains efficacy while Visudyne(R)-PDT becomes less effective as stromal content increases.

bioRxiv · Nov 9, 2021 · PreprintCancer Biology

Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma

T. Hasan, S. P. Caragher, J. M. Shireman, C. H. Park, F. Atashi, S. Baisiwala, G. Lee, D. Guo, M. Wu, J. Y. Wang, M. Dey, M. S. Lesniak, C. M. Horbinski, C. D. James, A. U. Ahmed

This study shows IL-8 promotes cellular plasticity and therapeutic resistance in glioblastoma by altering epigenetic marks and enhancing cancer initiating cell properties.

bioRxiv · Nov 16, 2018Cancer Biology