Author

M. A. Saad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

T. Hasan· 3 shared A. A. Ali· 1 shared A. A. Khattab· 1 shared A. A. Sweeney· 1 shared A. Palanisami· 1 shared A. T. Onawole· 1 shared B. Q. Spring· 1 shared E. M. Kercher· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersCancer Biology

T. Hasan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Dual Function Antibody Conjugate Enabled Photoimmunotherapy Complements Fluorescence and Photoacoustic Imaging of Head and Neck Cancer Spheroids

M. A. Saad, S. Grimaldo-Garcia, A. A. Sweeney, S. Mallidi, T. Hasan

This paper evaluates a dual function antibody conjugate for imaging and treating head and neck cancer spheroids, showing improved detection with photoacoustic imaging and effective PIT response.

bioRxiv · Jan 30, 2023Cancer Biology

Sparse-spectral microendoscopy for real-time visualization of tumor cell phenotype and microenvironment spatial heterogeneity in vivo

B. Q. Spring, A. Palanisami, M. A. Saad, E. M. Kercher, R. T. Lang, R. C. Harman, J. Sutin, Z. Mai, T. Hasan

This paper introduces a real-time imaging technique to visualize tumor cell phenotype and microenvironment spatial heterogeneity in vivo, revealing spatial correlations and treatment responses.

bioRxiv · Jun 17, 2022 · PreprintBioengineering

Photoimmunotherapy retains its anti-tumor efficacy with increasing stromal content in heterotypic pancreatic cancer spheroids

M. A. Saad, W. Zhung, M. E. Stanley, S. Formica, S. G. Garcia, G. Obaid, T. Hasan

This study evaluates photoimmunotherapy (PIT) and Visudyne(R)-PDT in PDAC spheroids with varying stromal content, showing PIT retains efficacy while Visudyne(R)-PDT becomes less effective as stromal content increases.

bioRxiv · Nov 9, 2021 · PreprintCancer Biology

Safety and Immunogenicity Evaluation of Inactivated whole-virus-SARS-COV-2 In Mice As Emerging Vaccine Development In Egypt

A. A. Ali, M. A. Saad, I. Ryan, M. Amin, M. I. Shindy, W. A. Hassan, M. Samir, A. A. Khattab, S. S. Abdelgayed, M. G. Seadawy, F. M. Fahmy, K. Amer

This study evaluates the safety and immunogenicity of an inactivated SARS-CoV-2 vaccine in mice, showing high antibody titers and complete protection against viral challenge.

bioRxiv · Mar 1, 2021Immunology

Computational Screening of Potential Inhibitors of Desulfobacter postgatei for Pyrite Scale Prevention in Oil and Gas Wells

I. A. Hussein, A. T. Onawole, M. A. Saad, H. I. Nimir, M. E. M. Ahmer

This paper identifies three potential inhibitors of ATP sulfurylase in Desulfobacter postgatei through virtual screening, with compound C showing the best safety and efficacy for preventing pyrite scale formation in oil and gas wells.

bioRxiv · May 22, 2018Biochemistry