Author

S. G. Rzuczek

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Cell Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1

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A. J. Angelbello· 1 shared A. S. Jun· 1 shared C. A. Thornton· 1 shared I. Yildirim· 1 shared J. L. Chen· 1 shared K. W. Wang· 1 shared M. D. Disney· 1 shared M. Roy· 1 shared

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2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. J. Angelbello

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1 paper

Recent·Most cited

Cell BiologybioRxivMay 11, 2020

A small molecule that binds an RNA repeat expansion stimulates its decay via the exosome complex

A. J. Angelbello, R. I. Benhamou, S. G. Rzuczek…·M. D. Disney

A small molecule binds an RNA repeat expansion, reversing disease defects in DM1 and FECD by either disabling gain-of-function or stimulating exosome-mediated decay.

DOI 10.1016/j.chembiol.2020.10.007

humanmultiome