CUL-6/cullin ubiquitin ligase-mediated degradation of HSP-90 by intestinal lysosomes promotes thermotolerance
M. Bardan Sarmiento, S. Gang, P. van Oosten-Hawle, E. Troemel
This study shows that CUL-6 ubiquitin ligase promotes thermotolerance by degrading HSP-90 in intestinal lysosomes, independent of HSF-1.
bioRxiv · Dec 21, 2023Cell Biology