Author

S. Gies

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Rasouli· 1 shared Alejandro Martin-TrujilloiD· 1 shared Andrew J. SharpiD· 1 shared Arianna TucciiD· 1 shared B. Walch-Rueckheim· 1 shared Benedict PateniD· 1 shared Bharati Jadhav· 1 shared Clarissa RoccaiD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiophysics

A. Rasouli

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3 papers

Recent·Most cited

Th17 cells target the metabolic miR-142-5p-SDHC/SDHD axis promoting invasiveness and progression of cervical cancers

M. Pohlers, S. Gies, T. Taenzer, R. Stroeder, L. Theobald, N. Ludwig, Y.-J. Kim, R. Bohle, E. F. Solomayer, E. Meese, M. Hart, B. Walch-Rueckheim

This study identifies a Th17 cell-driven miR-142-5p-SDHC/SDHD axis that enhances cervical cancer migration and invasion, with clinical correlations to metastasis and survival.

bioRxiv · Jun 29, 2023 · PreprintCancer Biology

A phenome-wide association study of methylated GC-rich repeats identifies a GCC repeat expansion in AFF3 as a significant cause of intellectual disability

Bharati Jadhav, Paras Garg, Joke J.F.A. van Vugt, Kristina Ibáñez, Delia Gagliardi, William Lee, Mariya Shadrina, Tom Mokveld, Egor Dolzhenko, Alejandro Martin-Trujillo, S. Gies, Clarissa Rocca, Mafalda Barbosa, Miten Jain, Nayana Lahiri, , Andrew J. Sharp

The paper identifies a GCC repeat expansion in AFF3 as a significant cause of intellectual disability through a phenome-wide association study using DNA methylation profiling and UK Biobank data.

medRxiv · May 3, 2023 · PreprintGenetic & Genomic Medicine

Proton-driven alternating access in a spinster transporter, an emerging family of broad-specificity efflux pumps

R. Dastvan, A. Rasouli, S. Dehghani-Ghahnaviyeh, S. Gies, E. Tajkhorshid

This study identifies conformational states and proton-coupled dynamics of a bacterial Spns transporter, revealing its role in multidrug resistance and substrate specificity.

bioRxiv · Mar 3, 2022 · PreprintBiophysics