MicrobiologyInternational Journal for Parasitology: Drugs and Drug ResistancePeer-reviewed
Suramin action in African trypanosomes involves a RuvB-like DNA helicase
A. Albisetti, S. Hälg, M. Zoltner…·N. Wiedemar
This paper identifies a DNA helicase, RuvBL1, as a key target of suramin in African trypanosomes, showing that mutations in this helicase confer resistance to the drug.