Author

N. Wiedemar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

P. Maeser· 2 shared A. Albisetti· 1 shared A. Hempelmann· 1 shared A. Passecker· 1 shared C. E. Stebbins· 1 shared E. Hitz· 1 shared F. N. Papavasiliou· 1 shared H. Hashemi· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

P. Maeser

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Author profile →

3 papers

Recent·Most cited

Suramin action in African trypanosomes involves a RuvB-like DNA helicase

A. Albisetti, S. Hälg, M. Zoltner, P. Mäser, N. Wiedemar

This paper identifies a DNA helicase, RuvBL1, as a key target of suramin in African trypanosomes, showing that mutations in this helicase confer resistance to the drug.

International Journal for Parasitology: Drugs and Drug Resistance · Dec 1, 2023Peer-reviewedMicrobiology

The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

E. Hitz, N. Wiedemar, A. Passecker, N. M. B. Brancucci, I. Vakonakis, P. Maeser, T. S. Voss

This study identifies PfPDK1 as an essential upstream activator of PfPKAc in malaria parasites, crucial for parasite survival and a potential drug target.

bioRxiv · May 27, 2021Microbiology

A Parasite Coat Protein Binds Suramin to Confer Drug Resistance

J. Zeelen, M. van Straaten, J. Verdi, A. Hempelmann, H. Hashemi, K. Perez, P. D. Jeffrey, S. Haelg, N. Wiedemar, P. Maeser, F. N. Papavasiliou, C. E. Stebbins

This study identifies that the trypanosome VSGsur protein binds suramin, conferring drug resistance, and shows this interaction is critical for resistance.

bioRxiv · Jun 4, 2020 · PreprintMicrobiology