Anti-nuclear antibody (ANA) detection in culture supernatant of cloned B cells
S. Haque, M. Watanabe, Y. Atisha-Fregoso, B. Diamond
The paper develops a method to detect ANA at low concentrations in single B cell cultures, enabling analysis of ANA reactivity from naive B cells of healthy individuals and autoimmune patients.
bioRxiv · May 12, 2023 · PreprintImmunology