Author

S. I. O'Rahilly

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Cell Biology· 1

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Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

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A. Alvarez-Guaita· 1 shared A. Haider· 1 shared D. B. Savage· 1 shared F. Scurria· 1 shared I. Luijten· 1 shared J. P. Mann· 1 shared J. Prudent· 1 shared L. C. Tabara· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperCell Biology

A. Alvarez-Guaita

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1 paper

Recent·Most cited

Cell BiologybioRxivSep 20, 2022

A mouse model of human mitofusin 2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion

J. P. Mann, X. Duan, A. Alvarez-Guaita…·D. B. Savage

This study uses a mouse model to show that a MFN2 mutation causes adipose-specific mitochondrial stress and reduced leptin secretion, linking mitochondrial dysfunction to metabolic disease.

DOI 10.7554/elife.82283

mouseelectronic health records

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