The cyclic nitroxide antioxidant 4-methoxy-TEMPO decreases mycobacterial burden in vivo through host and bacterial targets
H. D. Black, W. Xu, E. Hortle, S. I. Robertson, W. J. Britton, A. Kaur, E. J. New, P. K. Witting, B. Chami, S. Oehlers
This study shows that 4-methoxy-TEMPO reduces mycobacterial burden in zebrafish by targeting both host and bacterial redox mechanisms.
bioRxiv · Nov 11, 2018Microbiology