Characterization of SARS-CoV-2 Convalescent Patients' Serological Repertoire Reveals High Prevalence of Iso-RBD Antibodies
N. C. Curtis, S. Shin, A. P. Hederman, R. I. Connor, W. F. Wieland-Alter, S. Ionov, J. Boylston, J. Rose, M. Sakharkar, D. B. Dorman, J. A. Dessaint, L. L. Gwilt, A. R. Crowley, J. Feldman, B. M. Hauser, , J. Lee
This study characterizes the serological repertoire of SARS-CoV-2 convalescent patients, revealing a high prevalence of iso-RBD antibodies that do not recognize prefusion-stabilized S, and shows that vaccination with prefusion-stabilized S reduces their prevalence.
bioRxiv · Sep 8, 2023 · PreprintImmunology