Author

A. P. Hederman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

M. E. Ackerman· 2 shared A. Ashare· 1 shared A. E. Finzi· 1 shared A. G. Schmidt· 1 shared A. R. Crowley· 1 shared B. M. Hauser· 1 shared D. B. Dorman· 1 shared D. N. Nguyen· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

M. E. Ackerman

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Characterization of SARS-CoV-2 Convalescent Patients' Serological Repertoire Reveals High Prevalence of Iso-RBD Antibodies

N. C. Curtis, S. Shin, A. P. Hederman, R. I. Connor, W. F. Wieland-Alter, S. Ionov, J. Boylston, J. Rose, M. Sakharkar, D. B. Dorman, J. A. Dessaint, L. L. Gwilt, A. R. Crowley, J. Feldman, B. M. Hauser, , J. Lee

This study characterizes the serological repertoire of SARS-CoV-2 convalescent patients, revealing a high prevalence of iso-RBD antibodies that do not recognize prefusion-stabilized S, and shows that vaccination with prefusion-stabilized S reduces their prevalence.

bioRxiv · Sep 8, 2023 · PreprintImmunology

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

Y. Chen, L. Sun, I. Ullah, G. Beaudoin-Bussieres, S. P. Anand, A. P. Hederman, W. D. Tolbert, R. Sherburn, D. N. Nguyen, L. Marchitto, S. Ding, D. Wu, Y. Luo, S. Gottumukkala, S. Moran, , M. Pazgier

The paper develops ACE2-Fc molecules that neutralize SARS-CoV-2 and show Fc-effector activity, effectively treating lethal infection in mice.

bioRxiv · Nov 24, 2021Microbiology