Author

S. Irshad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Organism:mouse· 1

Frequent Co-Authors

A. A. Ritchie· 1 shared A. Bills· 1 shared A. Ligeza· 1 shared A. S. Ng· 1 shared A. Silver· 1 shared A. V. Predeus· 1 shared B. Cakir· 1 shared D. Sculthorpe· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. A. Ritchie

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Author profile →

2 papers

Recent·Most cited

GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche via stromal remodelling

E. J. Mulholland, H. L. Belnoue-Davis, G. N. Valbuena, N. Gunduz, A. Ligeza, S. Biswas, E. Gil Vasquez, S. Omwenga, N. Nasreddin, M. Hodder, L. M. Wang, S. Irshad, A. S. Ng, E. K. Jennings, K. S. Midwood, , S. J. Leedham

Pathological epithelial GREM1 expression induces therapeutically reversible ectopic stem cell niches through stromal remodelling.

bioRxiv · Apr 28, 2024 · PreprintCancer Biology

Generation of transplantable and biologically responsive colonic tissue from human induced pluripotent stem cells using a rapid co-differentiation platform.

W. Dalleywater, A. V. Predeus, B. Cakir, P. Mazin, J. Vadakekolathu, S. Rutella, M. L. Meakin, A. A. Ritchie, S. Montazid, S. Cuevas Ocana, N. Holmes, V. Wright, F. Seng, A. Bills, D. Sculthorpe, , M. Ilyas

This paper develops a co-differentiation platform using human iPSCs to generate transplantable colonic tissue that mimics native mucosa and responds to biological signals.

bioRxiv · Dec 8, 2023 · PreprintCell Biology