Author

E. J. Mulholland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. J. Leedham· 3 shared G. N. Valbuena· 2 shared J. E. East· 2 shared N. Nasreddin· 2 shared V. H. Koelzer· 2 shared A. Antanaviciute· 1 shared A. D. Campbell· 1 shared A. Easton· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersPathology

S. J. Leedham

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Author profile →

3 papers

Recent·Most cited

Extended correlation functions for spatial analysis of multiplex imaging data

J. A. Bull, E. J. Mulholland, S. J. Leedham, H. M. Byrne

This paper introduces three extensions to the cross-pair correlation function for spatial analysis of multiplex imaging data, demonstrating their application on synthetic and biological datasets.

bioRxiv · Jun 20, 2023Pathology

Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture

E. Gil Vazquez, N. Nasreddin, G. N. Valbuena, E. J. Mulholland, H. L. Belnoue-Davis, H. Eggington, R. O. Schenck, V. M. Wouters, P. Wirapati, K. Gilroy, T. R. M. Lannagan, D. J. Flanagan, A. K. Najumudeen, S. Omwenga, A. M. B. McCorry, , S. J. Leedham

The paper examines stem cell population dynamics in colorectal tumors, showing that CBC-RSC admixture correlates with mutations and microenvironmental changes, and is linked to chemoresistance.

bioRxiv · Jun 11, 2022Cancer Biology

BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration

M. A. Koppens, H. Davis, G. N. Valbuena, E. J. Mulholland, N. Nasreddin, M. Colombe, A. Antanaviciute, S. Biswas, M. Friedrich, L. Lee, Oxford IBD Cohort Investigators, L. M. Wang, V. H. Koelzer, J. E. East, A. Simmons, , S. J. Leedham

This study shows that Grem1 antagonizes BMP signaling to regulate epithelial cell fate during intestinal regeneration.

bioRxiv · Jan 6, 2021Cell Biology