Circulatory exosomes from COVID-19 patients trigger NLRP3 inflammasome in endothelial cells
S. Sur, r. steele, S. Isbell, R. Ray, R. B. Ray
This study shows that exosomes from severe COVID-19 patients activate the NLRP3 inflammasome in endothelial cells, leading to increased IL-1β secretion.
bioRxiv · Feb 3, 2022 · PreprintImmunology