Author

S. J. Karpen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:metabolomics· 1

Frequent Co-Authors

P. A. Dawson· 2 shared A. Balasubramanian· 1 shared A. Delmas-Eliason· 1 shared A. Rao· 1 shared A. Rodriguez-Palacios· 1 shared C. D. Fuchs· 1 shared C. J. Shu· 1 shared C. L. Hegner· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPhysiology

P. A. Dawson

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Author profile →

2 papers

Recent·Most cited

Quantifying forms and functions of intestinal bile acid pools in mice

K. Sudo, A. Delmas-Eliason, S. Soucy, K. E. Barrack, J. Liu, A. Balasubramanian, C. J. Shu, M. James, C. L. Hegner, H. D. Dionne, A. Rodriguez-Palacios, H. Krause, G. A. O'Toole, S. J. Karpen, P. A. Dawson, , M. S. Sundrud

The paper quantifies ileal bile acid pools in mice and shows that Asbt-mediated transport dominates their size and composition, with loss of Asbt reducing pool size and altering transcriptional responses.

bioRxiv · Feb 16, 2024 · PreprintPhysiology

Active Enterohepatic Cycling is Not Required for the Choleretic Actions of 24-norUrsodeoxycholic Acid in Mice

J. Li, J. K. Truong, K. Pachura, A. Rao, S. Gambeer, C. D. Fuchs, S. J. Karpen, M. J. Trauner, P. A. Dawson

This study shows that norUDCA induces bile flow and bicarbonate secretion in mice without requiring ASBT or OST, suggesting these transporters are not directly involved in its choleretic actions.

bioRxiv · Mar 6, 2021 · PreprintCell Biology