Author

S. J. Tsai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Assay:multiome· 1

Frequent Co-Authors

A. Cox· 2 shared C. Guo· 2 shared S. Gould· 2 shared A. Kell· 1 shared A. Pekosz· 1 shared A. Sedgwick· 1 shared C. G. Guo· 1 shared C. Landaverde· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersPhysiology

A. Cox

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SARS-COV-2 induced Diarrhea is inflammatory, Ca2+ Dependent and involves activation of calcium activated Cl channels

M. Donowitz, C.-M. Tse, K. Dokladny, M. Rawat, I. Hurwitz, C. Ye, A. Kell, R. Lin, S. Lee, C. G. Guo, S. J. Tsai, A. Cox, S. Gould, J. In, S. B. Bradfute, , O. Kovbasnjuk

This study investigates the pathophysiology of SARS-CoV-2-induced diarrhea, showing it is inflammatory, calcium-dependent, and involves activation of calcium-activated chloride channels.

bioRxiv · Apr 27, 2021 · PreprintPhysiology

The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike

C. Guo, S. J. Tsai, Y. Ai, M. Li, A. Pekosz, A. Cox, N. Atai, S. Gould

This study shows the D614G mutation in SARS-CoV-2 spike enhances lysosomal trafficking and accumulation, contributing to increased infectivity and transmission.

bioRxiv · Dec 8, 2020Cell Biology

Exosome-Mediated mRNA Delivery For SARS-CoV-2 Vaccination

S. J. Tsai, C. Guo, A. Sedgwick, S. Kanagavelu, J. Nice, S. Shetty, C. Landaverde, N. A. Atai, S. J. Gould

This paper develops exosome-based mRNA vaccines that express SARS-CoV-2 antigens, showing long-lasting immune responses and fewer adverse effects than lipid nanoparticles.

bioRxiv · Nov 6, 2020 · PreprintImmunology