Author

S. K. Pal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 4 Biophysics· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 2 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:multiome· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Adhikari· 8 shared S. Mondal· 8 shared R. Ghosh· 6 shared S. Darbar· 6 shared P. Biswas· 5 shared U. Pal· 5 shared A. K. Das· 4 shared M. Das· 4 shared

Activity by Year

2020-2021 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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8 shared papersPharmacology & Toxicology

A. Adhikari

Mutual co-authors in cluster

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8 papers

Recent·Most cited

Essential Loop Dynamics Modulates Catalytic Activity in α-Chymotrypsin

P. Biswas, U. Pal, A. Adhikari, S. Mondal, R. Ghosh, D. Mukherjee, P. D. T. Saha-Dasgupta, D. S. S. Choudhury, P. D. R. Das, S. K. Pal

This study investigates how essential loop dynamics in alpha-chymotrypsin affect its catalytic activity using optical spectroscopy and molecular dynamics simulations.

bioRxiv · Aug 11, 2021Biophysics

A Combined Spectroscopic and Molecular Modeling Study on Structure-Function-Dynamics under Chemical Modification: Alpha-Chymotrypsin with Formalin Preservative

P. Biswas, A. Adhikari, U. Pal, S. Mondal, D. Mukherjee, R. Ghosh, T. Saha-Dasgupta, S. S. Chowdhury, R. Das, S. K. Pal

This study examines how formalin modifies alpha-chymotrypsin's structure and function, showing reduced catalytic activity and altered substrate binding due to cross-linking.

bioRxiv · Jul 24, 2021Biophysics

Redox Nanomedicine Cures Chronic Kidney Disease (CKD) by Mitochondrial Reconditioning

A. Adhikari, S. Mondal, T. Chatterjee, M. Das, P. Biswas, S. Darbar, H. Alessa, A. Sayqal, S. A. Ahmed, A. K. Das, M. Bhattacharyya, S. K. Pal

This study demonstrates that a redox nanomedicine, C-Mn3O4 NPs, treats CKD by restoring mitochondrial function and redox balance in animal models.

bioRxiv · Mar 14, 2021Pharmacology & Toxicology

Redox Buffering Capacity of Nanomaterials as an Index of ROS-based Therapeutics and Toxicity: A Preclinical Animal Study

A. Adhikari, S. Mondal, M. Das, R. Ghosh, P. Biswas, S. Darbar, A. K. Das, S. Bhattacharya, D. Pal, A. K. Mallick, S. K. Pal

This study evaluates the redox buffering capacity of nanomaterials to assess their therapeutic potential and toxicity in a preclinical animal model.

bioRxiv · Mar 14, 2021Pharmacology & Toxicology

Development of Tribo-Electroceutical Fabrics for Potential Application in Self-sanitizing Personal Protective Equipment (PPE)

S. Bayan, A. Adhikari, U. Pal, R. Ghosh, S. Mondal, S. Darbar, T. Saha-Dasgupta, S. K. Ray, S. K. Pal

This paper develops tribo-electroceutical fabrics that generate hypochlorite ions to sanitize PPE surfaces, reducing microbial infection risk.

bioRxiv · Feb 23, 2021Microbiology

Nanoceutical Fabric Prevents COVID-19 Spread through Expelled Respiratory Droplets: A Combined Computational, Spectroscopic and Anti-microbial Study

A. Adhikari, U. Pal, S. Bayan, S. Mondal, R. Ghosh, S. Darbar, T. Saha-Dasgupta, S. K. Ray, S. K. Pal

The paper develops a nanoceutical cotton fabric with zinc oxide nanoflowers to prevent COVID-19 spread through respiratory droplets by trapping and denaturing SARS-CoV-2 spike proteins.

bioRxiv · Feb 20, 2021Microbiology

A Nanoceutical Agent for Chemoprevention of Bilirubin Encephalopathy

A. Adhikari, V. K. Bhutani, S. Mondal, M. Das, S. Darbar, R. Ghosh, N. Polley, A. K. Das, S. S. Bhattacharya, A. K. Mallick, S. K. Pal

This paper reports on the development and testing of citrate-functionalized Mn3O4 nanoparticles for the prevention of bilirubin encephalopathy in a mouse model of neonatal hyperbilirubinemia.

bioRxiv · Dec 31, 2020 · PreprintPharmacology & Toxicology

Incorporation of a Biocompatible Nanozyme in Cellular Antioxidant Enzyme Cascade Reverses Huntington's Like Disorder in Preclinical Model

A. Adhikari, S. Mondal, M. Das, P. Biswas, U. Pal, S. Darbar, S. S. Bhattacharya, D. Pal, T. Saha-Dasgupta, A. K. Das, A. K. Mallick, S. K. Pal

This paper demonstrates that a biocompatible nanozyme can reverse Huntington's-like disorder in a preclinical model by mimicking glutathione peroxidase and integrating into the cellular antioxidant cascade.

bioRxiv · Sep 23, 2020Pharmacology & Toxicology