Systemic immune response profiling with SYLARAS implicates a role for CD45R/B220+ CD8+ T cells in glioblastoma immunology
G. J. Baker, J. L. Muhlich, S. K. Palaniappan, J. K. Moore, S. H. Davis, S. Santagata, P. K. Sorger
The paper introduces SYLARAS, a tool for immune response profiling, and shows CD45R/B220+ CD8+ T cells are depleted in circulation and accumulate in glioblastoma tumors in mice, with similar cells found in human GBM.
bioRxiv · Oct 22, 2019 · PreprintImmunology