Phosphatidylinositol 4-kinase II β down regulation induces ER stress mediated ROS generation and increases radio-sensitivity in MCF-7.
S. Chaudhry, R. Checker, M. Thoh, S. K. Sandur, G. Subrahmanyam
This study shows that downregulating PtdIns 4-kinase II β increases ER stress, ROS, and apoptosis in MCF-7 cells, enhancing their sensitivity to radiation.
bioRxiv · Oct 3, 2023 · PreprintCell Biology