Author

S. Kasiri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. Kim· 2 shared L. Girard· 2 shared U. Marriam· 2 shared A. K. Kaushik· 1 shared A. N. Wilson· 1 shared A. Reczek· 1 shared B. Chen· 1 shared B. Faubert· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

J. Kim

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2 papers

Recent·Most cited

The hexosamine biosynthesis pathway is a targetable liability in lung cancers with concurrent KRAS and LKB1 mutations.

J. Kim, F. Cai, B. Ko, C. Yang, H. M. Lee, N. Muhammad, K. Li, M. Haloul, W. Gu, B. Faubert, A. K. Kaushik, L. Cai, S. Kasiri, U. Marriam, K. Nham, , R. J. DeBerardinis

The paper identifies the hexosamine biosynthesis pathway as a metabolic vulnerability in KRAS/LKB1 mutant lung cancers and shows GFPT2 inhibition reduces tumor growth.

bioRxiv · Apr 13, 2020 · PreprintCancer Biology

Stromal Hedgehog pathway activation by IHH suppresses lung adenocarcinoma growth and metastasis by limiting reactive oxygen species

S. Kasiri, B. Chen, A. N. Wilson, A. Reczek, S. Mazambani, J. Gadhvi, E. Noel, U. Marriam, B. Mino, W. Lu, L. Girard, L. Solis, K. Luby-Phelps, J. Bishop, J.-W. Kim, J. Kim

This study shows that IHH activates the stromal Hedgehog pathway to suppress lung adenocarcinoma growth and metastasis by reducing reactive oxygen species.

bioRxiv · Aug 27, 2019Cancer Biology