Characterization and Validation of a Middle-Down Hydrophobic Interaction Chromatography Method to Monitor Methionine Oxidation in IgG1
S. Khalil, N. Patel, F. Bevillard-Kumar, C. Chery, W. Burkitt, J. O Hara, A. Gervais
This paper develops and validates a middle-down hydrophobic interaction chromatography method to monitor methionine oxidation in IgG1, demonstrating its specificity, linearity, precision, and accuracy.
bioRxiv · Feb 1, 2023Biochemistry