Integration of pathway, cellular and genetic context reveals principles of synthetic lethality that affect reproducibility
A. A. Ku, S. Kongara, H.-M. Hu, X. Zhao, D. Wu, F. McCormick, A. Balmain, S. Bandyopadhyay
The paper identifies principles for improving synthetic lethality reproducibility by integrating pathway, cellular, and genetic context in KRAS-mutant cells.
bioRxiv · Mar 28, 2019 · PreprintCancer Biology