Author

A. A. Ku

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

F. McCormick· 2 shared S. Bandyopadhyay· 2 shared A. Balmain· 1 shared A. L. Wolfe· 1 shared C. B. Lebrilla· 1 shared D. Wu· 1 shared E. Toska· 1 shared H.-M. Hu· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

F. McCormick

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2 papers

Recent·Most cited

UDP-glucose pyrophosphorylase 2, a regulator of glycosylation and glycogen, is essential for pancreatic cancer growth

A. L. Wolfe, Q. Zhou, E. Toska, J. Galeas, A. A. Ku, R. P. Koche, S. Bandyopadhyay, M. Scaltriti, C. B. Lebrilla, F. McCormick, S. E. Kim

This study identifies UGP2 as essential for pancreatic cancer growth by regulating glycogen and N-glycosylation, with potential therapeutic implications.

bioRxiv · Oct 13, 2020 · PreprintCancer Biology

Integration of pathway, cellular and genetic context reveals principles of synthetic lethality that affect reproducibility

A. A. Ku, S. Kongara, H.-M. Hu, X. Zhao, D. Wu, F. McCormick, A. Balmain, S. Bandyopadhyay

The paper identifies principles for improving synthetic lethality reproducibility by integrating pathway, cellular, and genetic context in KRAS-mutant cells.

bioRxiv · Mar 28, 2019 · PreprintCancer Biology