Author

H.-M. Hu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

S. Bandyopadhyay· 3 shared X. Zhao· 3 shared S. Kaushik· 2 shared A. A. Ku· 1 shared A. Balmain· 1 shared A. Barthelet· 1 shared A. Simmons· 1 shared D. Ciznadija· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCancer Biology

S. Bandyopadhyay

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Author profile →

3 papers

Recent·Most cited

A tyrosine kinase protein interaction map reveals targetable EGFR network oncogenesis in lung cancer

S. Kaushik, F. Haderk, X. Zhao, H.-M. Hu, K. N. Shah, G. M. Jang, V. Olivas, S. Nanjo, V. B. Masto, D. Ciznadija, I. Sloma, E. Gross, S. L. Weinrich, J. R. Johnson, T. G. Bivona, , S. Bandyopadhyay

The paper constructs a tyrosine kinase protein interaction map, revealing EGFR network oncogenesis in 19% of EGFR wild-type lung cancers, which is targetable with EGFR inhibitors.

bioRxiv · Jul 2, 2020 · PreprintCancer Biology

Integration of pathway, cellular and genetic context reveals principles of synthetic lethality that affect reproducibility

A. A. Ku, S. Kongara, H.-M. Hu, X. Zhao, D. Wu, F. McCormick, A. Balmain, S. Bandyopadhyay

The paper identifies principles for improving synthetic lethality reproducibility by integrating pathway, cellular, and genetic context in KRAS-mutant cells.

bioRxiv · Mar 28, 2019 · PreprintCancer Biology

A quantitative chemotherapy genetic interaction map reveals new factors associated with PARP inhibitor resistance

H.-M. Hu, X. Zhao, S. Kaushik, L. Robillard, A. Barthelet, K. K. Lin, A. Simmons, M. Raponi, T. C. Harding, S. Bandyopadhyay

This paper creates a quantitative chemical-genetic interaction map in human cells to identify factors affecting chemotherapy response and resistance.

bioRxiv · Aug 3, 2017Cancer Biology