A nexus of intrinsic dynamics underlies translocase priming
S. Krisnamurthy, N. Eleftheriadis, K. Karathanou, J. H. Smit, A. Portaliou, K. E. Chatzi, S. Karamanou, A.-N. Bondar, G. Gouridis, A. Economou
This study identifies a dynamic nexus in SecA that primes the Sec translocase for preprotein binding through conserved structural motions and interactions.
bioRxiv · Jan 18, 2021Biochemistry